OC-Sensor is an immunochemical test for the quantitative detection of occult human haemoglobin in stool samples. The immunoturbidimetric analysis requires established clinical laboratory technology.
In the case of diseases that involve haemorrhagic lesions in the gut, such as intestinal tumours or their precursors for instance, the quantity of haemoglobin in the stool is normally increased. Therefore determining the quantity of haemoglobin in the stool represents an effective screening method for the early detection of colorectal cancer.
Test principle OC-Sensor
The test method is based on a latex agglutination reaction. Latex particles are used which are paired with specific polyclonal antibodies against human haemoglobin (anti-human-HbA0). These form specific bonds with the haemoglobin from the stool sample and there follows an agglutination of latex particles, which can be detected turbidimetrically (photometrically).
Analysis and evaluation are fully automated and standardised through use of an OC-Sensor analysis device; the quantitative, measured results are objectively determined and documented by means of photometric (optical) analysis technology.
Internal control material enables the laboratory user to have immediate and independent monitoring and control of the test system used.
FIT-Screening with OC-Sensor
- Specific and sensitive immunochemical evidence of human haemoglobin
- Quantitative determination of the haemoglobin concentration in the stool sample
- Standardised and quality-assured analysis: fully automated (with no manual sample preparation), objective photometric determining of the measured results.